| (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Basic information |
| Product Name: | (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid |
| Synonyms: | (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-(Tert-butoxycarbonyl)-2-azabicyclo-[2.2.1]-heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97%;2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, 2-(1,1-diMethylethyl) ester, (1R,3S,4S)-;(1R,3S,4S)-3-[(2-methylpropoxy)carbonyl]-2-azabicyclo[2.2.1]heptane-2-carboxylic acid;Ledipasvir INT 2;Ledipasvir Impurity 14 |
| CAS: | 291775-59-2 |
| MF: | C12H19NO4 |
| MW: | 241.28 |
| EINECS: | 808-164-2 |
| Product Categories: | Heterocycles |
![(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Structure](https://www.chemicalbook.com/CAS/GIF/291775-59-2.gif) |
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| (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Chemical Properties |
| Melting point | 147-152 °C |
| Boiling point | 371.0±25.0 °C(Predicted) |
| density | 1.232±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 4.05±0.20(Predicted) |
| form | powder |
| optical activity | [α]22/D -170±10°, c = 1 in chloroform |
| InChIKey | IFAMSTPTNRJBRG-YIZRAAEISA-N |
| Safety Information |
| Hazard Codes | Xi,N |
| Risk Statements | 61-36/37/38 |
| Safety Statements | 53-26-61 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Usage And Synthesis |
| Uses | (1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid is a building block in the synthesis of Ledipasvir, a potent, once-??daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants. |
